NCOR1 Polyclonal Antibody
RD84247A
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetNCOR1
Overview
- SupplierReddot Biotech
- Product NameNCOR1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9611
- Target nameNCOR1
- Target descriptionnuclear receptor corepressor 1
- Target synonymshN-CoR; N-CoR; N-CoR1; nuclear receptor corepressor 1; PPP1R109; protein phosphatase 1, regulatory subunit 109; thyroid hormone- and retinoic acid receptor-associated corepressor 1; TRAC1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203