NCT-501 hydrochloride [2080306-22-3]

TargetMol Chemicals

NCT-501 hydrochloride [2080306-22-3]

44

2080306-22-3

Chemical

Research Use Only

NCT-501 hydrochloride

C21H33ClN6O3

452.98

NCT-501 hydrochloride is a highly potent and selective inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), which is based on theophylline. It effectively inhibits hALDH1A1 with an IC50 value of 40 nM, exhibiting superior selectivity towards hALDH1A1 compared to other ALDH isozymes and dehydrogenases such as hALDH1B1, hALDH3A1, and hALDH2 (with IC50 values exceeding 57 microM).

3 years

Cl.CC(C)CCn1c(CN2CCN(CC2)C(=O)C2CC2)nc2n(C)c(=O)n(C)c(=O)c12

-20°C

12352200