NDC80 Antibody, HRP conjugated
CSB-PA015601LB01HU
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetNDC80
Overview
- SupplierCusabio
- Product NameNDC80 Antibody, HRP conjugated
- Delivery Days Customer20
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateHRP
- Gene ID10403
- Target nameNDC80
- Target descriptionNDC80 kinetochore complex component
- Target synonymsHEC; HEC1; highly expressed in cancer protein; highly expressed in cancer, rich in leucine heptad repeats; HsHec1; hsNDC80; kinetochore associated 2; kinetochore protein Hec1; kinetochore protein NDC80 homolog; kinetochore-associated protein 2; KNTC2; NDC80 homolog, kinetochore complex component; NDC80 kinetochore complex component homolog; retinoblastoma-associated protein HEC; TID3
- HostRabbit
- IsotypeIgG
- Protein IDO14777
- Protein NameKinetochore protein NDC80 homolog
- Scientific DescriptionActs as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203