NDI-034858 [2272904-53-5]

TargetMol Chemicals

NDI-034858 [2272904-53-5]

9

Chemical

Research Use Only

NDI-034858

C23H24N8O3

460.49

NDI-034858 (TAK-279) is a tyrosine kinase 2 (TYK2) inhibitor (Kd<200 pM) that targets the JH2 structural domain of Tyk2 for the treatment of autoimmune diseases caused by aberrant expression of IL12 and IL23.

3 years

CNc1cc(Nc2cccn(-c3ccccn3)c2=O)nc2c(cnn12)C(=O)N[C@@H]1CC[C@H]1OC

-20°C

12352200