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NDUFS4 antibody

GTX105662
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetNDUFS4
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Overview

  • Supplier
    GeneTex
  • Product Name
    NDUFS4 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4724
  • Target name
    NDUFS4
  • Target description
    NADH:ubiquinone oxidoreductase subunit S4
  • Target synonyms
    AQDQ, CI-18, CI-18 kDa, CI-AQDQ, MC1DN1, NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial, NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase), NADH-ubiquinone oxidoreductase 18 kDa subunit, complex I 18kDa subunit, complex I-AQDQ, mitochondrial respiratory chain complex I (18-KD subunit)
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO43181
  • Protein Name
    NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
  • Scientific Description
    This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Lim SC, Hroudová J, Van Bergen NJ, et al. Loss of mitochondrial DNA-encoded protein ND1 results in disruption of complex I biogenesis during early stages of assembly. FASEB J. 2016,30(6):2236-48. doi: 10.1096/fj.201500137R
    Read this paper