Necrostatin-1 [4311-88-0]
N1610
Estimated Purity≥99%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameNecrostatin-1 [4311-88-0]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥99%
- FormatSoluble in DMSO (10-25 mg/ml), 100% ethanol (6 mg/ml), and methanol (5 mg/ml).
- Scientific DescriptionRIP1 inhibitor.
- Storage Instruction-20°C
- UNSPSC12352200
References
- Zhu Y, Cui H, Gan H, et al. Necroptosis mediated by receptor interaction protein kinase 1 and 3 aggravates chronic kidney injury of subtotal nephrectomised rats. Biochem Biophys Res Commun. 2015 Jun 12;461(4):575-81. PMID: 25907058. Yin B, Xu Y, Wei RL, et al. Inhibition of receptor-interacting protein 3 upregulation and nuclear translocation involved in Necrostatin-1 protection against hippocampal neuronal programmed necrosis induced by ischemia/reperfusion injury. Brain Res. 2015 Jun 3;1609:63-71. PMID: 25801119. Steinwascher S, Nugues AL, Schoeneberger H, et al. Identification of a novel synergistic induction of cell death by Smac mimetic and HDAC inhibitors in acute myeloid leukemia cells. Cancer Lett. 2015 May 28. [Epub ahead of print]. PMID: 26028172.