Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA882076ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA882076ESR2HU at dilution of 1:100
NECTIN3 Antibody
CSB-PA882076ESR2HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetNECTIN3
Overview
- SupplierCusabio
- Product NameNECTIN3 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID25945
- Target nameNECTIN3
- Target descriptionnectin cell adhesion molecule 3
- Target synonymsCD113; CDW113; nectin 3; nectin-3; poliovirus receptor-related 3; poliovirus receptor-related protein 3; PPR3; PRR3; PVRL3; PVRR3
- HostRabbit
- IsotypeIgG
- Protein IDQ9NQS3
- Protein NameNectin-3
- Scientific DescriptionPlays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203