Nedaplatin [95734-82-0]

TargetMol Chemicals

Nedaplatin [95734-82-0]

9

95734-82-0

Chemical

Research Use Only

Nedaplatin

C2H8N2O3Pt

303.17

Nedaplatin (NSC-375101D) is a derivative of cisplatin and DNA damage agent for tumor colony forming units (IC50: 94 microM). Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand, nedaplatin forms reactive platinum complexes that bind to nucleophilic groups in DNA, resulting in intrastrand and interstrand DNA cross-links, apoptosis and cell death.

3 years

N.N.[Pt++].[O-]CC([O-])=O

-20°C

12352200