NEDD4 Polyclonal Antibody

Reddot Biotech

NEDD4 Polyclonal Antibody

5

ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

NEDD4

NEDD4 E3 ubiquitin protein ligase

cell proliferation-inducing gene 53 protein; E3 ubiquitin-protein ligase NEDD4; HECT-type E3 ubiquitin transferase NEDD4; NEDD4-1; neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase; receptor-potentiating factor 1; RPF1

Rabbit

IgG

This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.

Human

-20°C

12352203