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Western Blot Positive WB detected in: 293 whole cell lysate, Jurkat whole cell lysate, Hela whole cell lysate All lanes: NEDD4L antibody at 3microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 112, 105, 101, 99, 111, 110, 97 kDa Observed band size: 112 kDa
Western Blot Positive WB detected in: 293 whole cell lysate, Jurkat whole cell lysate, Hela whole cell lysate All lanes: NEDD4L antibody at 3microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 112, 105, 101, 99, 111, 110, 97 kDa Observed band size: 112 kDa
Western Blot Positive WB detected in: 293 whole cell lysate, Jurkat whole cell lysate, Hela whole cell lysate All lanes: NEDD4L antibody at 3microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 112, 105, 101, 99, 111, 110, 97 kDa Observed band size: 112 kDa

NEDD4L Antibody

Research Use Only
CSB-PA850411LA01HU
Cusabio
ApplicationsImmunoFluorescence, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetNEDD4L
Price on request
Packing Size
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More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    Cusabio
  • Product Name
    NEDD4L Antibody
  • Delivery Days Customer
    20
  • Applications
    ImmunoFluorescence, Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID23327
  • Target name
    NEDD4L
  • Target description
    NEDD4 like E3 ubiquitin protein ligase
  • Target synonyms
    E3 ubiquitin-protein ligase NEDD4-like; HECT-type E3 ubiquitin transferase NED4L; hNEDD4-2; NEDD4.2; NEDD4-2; neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase; PVNH7; RSP5; ubiquitin-protein ligase Rsp5
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ96PU5
  • Protein Name
    E3 ubiquitin-protein ligase NEDD4-like
  • Scientific Description
    E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFBR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, KCNH2, EAAT1 or CLC5 (PubMed:26363003). Promotes ubiquitination and degradation of SGK1 and TNK2. Ubiquitinates BRAT1 and this ubiquitination is enhanced in the presence of NDFIP1 (PubMed:25631046). Plays a role in dendrite formation by melanocytes (PubMed:23999003). Involved in the regulation of TOR signaling (PubMed:27694961).
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203