Nefazodone Hydrochloride [82752-99-6]
N1822
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameNefazodone Hydrochloride [82752-99-6]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- FormatSlightly soluble in water.
- Scientific Description5-HT2 antagonist, SERT and NET inhibitor, hERG K+ channel blocker.; BMY-13754, MJ-13754-1, Dutonin, Serzone
- Storage InstructionAmbient
- UNSPSC12352200
References
- Shin DS, Park MJ, Lee HA, et al. A novel assessment of nefazodone-induced hERG inhibition by electrophysiological and stereochemical method. Toxicol Appl Pharmacol. 2014 Feb 1;274(3):361-71. PMID: 24374264. Clayton AH, Montejo AL. Major depressive disorder, antidepressants, and sexual dysfunction. J Clin Psychiatry. 2006;67 Suppl 6:33-7. PMID: 16848675. Dremencov E, Gispan-Herman I, Rosenstein M, et al. The serotonin-dopamine interaction is critical for fast-onset action of antidepressant treatment: in vivo studies in an animal model of depression. Prog Neuropsychopharmacol Biol Psychiatry. 2004 Jan;28(1):141-7. PMID: 14687868. Eckler JR, Rabin RA, Winter JC. Nefazodone in the rat: mimicry and antagonism of [-]-DOM-induced stimulus control. Pharmacol Biochem Behav. 2003 May;75(2):405-10. PMID: 12873632.