Nefiracetam [77191-36-7]
N1721
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameNefiracetam [77191-36-7]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- Scientific DescriptionPyrrolidone; NMDA and mGluR5 agonist, N-type and L-type Ca2+ channel activator, alfa4bèta2 nAChR potentiator.; DM-9384
- Storage InstructionAmbient
- UNSPSC12352200
References
- Lu XC, Dave JR, Chen Z, et al. Nefiracetam attenuates post-ischemic nonconvulsive seizures in rats and protects neuronal cell death induced by veratridine and glutamate. Life Sci. 2013 Jun 13;92(22):1055-63. PMID: 23603142. Malykh AG, Sadaie MR. Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders. Drugs. 2010 Feb 12;70(3):287-312. PMID: 20166767. Moriguchi S, Han F, Shioda N, et al. Nefiracetam activation of CaM kinase II and protein kinase C mediated by NMDA and metabotropic glutamate receptors in olfactory bulbectomized mice. J Neurochem. 2009 Jul;110(1):170-81. PMID: 19457128. Kitano Y, Komiyama C, Makino M, et al. Anticonvulsant and neuroprotective effects of the novel nootropic agent nefiracetam on kainic acid-induced seizures in rats. Brain Res. 2005 Sep 28;1057(1-2):168-76. PMID: 16122714. Narahashi T, Moriguchi S, Zhao X, et al. Mechanisms of action of cognitive enhancers on neuroreceptors. Biol Pharm Bull. 2004 Nov;27(11):1701-6. PMID: 15516710. Yoshii M, Watabe S, Murashima YL, et al. Cellular mechanism of action of cognitive enhancers: effects of nefiracetam on neuronal Ca2+ channels. Alzheimer Dis Assoc Disord. 2000;14 Suppl 1:S95-102. PMID: 10850736.