Nelivaptan

MedChem Express

Nelivaptan [439687-69-1]

14

439687-69-1

98.35

C30H32ClN3O8S

630.11

Nelivaptan (SSR-149415) is a selective and orally active vasopressin V1b Receptor antagonist ( K i : 3.7 and 1.3 nM for native and recombinant rat V1b receptors, respectively). Nelivaptan inhibits arginine vasopressin (AVP)-induced Ca 2+ increase and corticotropin secretion. Nelivaptan can be used for research of stress and anxiety [1] .

O=S(N(C(C=C1)=C2C=C1Cl)C([C@@]2(C3=CC=CC=C3OC)N4[C@@H](C[C@@H](O)C4)C(N(C)C)=O)=O)(C(C(OC)=C5)=CC=C5OC)=O

2°C to 8°C

12352200