Nemazoline

MedChem Express

Nemazoline

9

Research Use Only

C10H11Cl2N3

244.12

Nemazoline (A-57219) is selective alpha-adrenergic agent with alpha 1 -agonist/ alpha 2 -antagonist activity, which is used as a nasal decongestant. Nemazoline produces decongestion by alpha 1 -mediated contraction of capacitance vessels, but not compromises blood flow by virtue of alpha 2 -antagonism. Nemazoline also blocks endogenous noradrenaline-mediated alpha 2 -constriction of the resistance vessels [1] .

NC1=C(C=C(C=C1Cl)CC2=NCCN2)Cl

12352200