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ProductsBack/Nemorosone [351416-47-2]

Nemorosone [351416-47-2]

Research Use Only
N176498
LKT Laboratories
Estimated Purity≥99%
Product group Chemicals
€ 583,00
25 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Nemorosone [351416-47-2]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥99%
  • Scientific Description
    Found in the propolis of honey bees.; Memorosone, 1-Benzoyl-3,5,7-tri-(3-methyl-2-butenyl)-4-hydroxy-8-dimethyl-bicyclo[3.3.1]-3-nonene-2,9-dione, 1-Benzoyl-4-hydroxy-8,8-dimethyl-3,5,7-tris-(3-methyl-but-2-enyl)-bicyclo[3.3.1]non-3-ene-2,9-dione, bicyclo[3.3.1]non-3-ene-2,9-dione, 1-benzoyl-4-hydroxy-8,8-dimethyl-3,5,7-tris(3-methyl-2-butenyl)-, (1R,5R,7S)-
  • Storage Instruction
    Stable in solid form. Unstable in solution.; -20°C
  • UNSPSC
    12352200

References

  • da Cunha MG, Rosalen PL, Franchin M, et al. Antiproliferative constituents of geopropolis from the bee Melipona scutellaris. Planta Med. 2016 Feb;82(3):190-194. PMID: 26544117. Wolf RJ, Hilger RA, Hoheisel JD, et al. In vivo activity and pharmocokinetics of nemorosone in pancreatic cancer xenografts. PLoS One. 2013 Sep 5;8(9):e74555. PMID: 24040280. Holtrup F, Bauer A, Fellenberg K, et al. Microarray analysis of nemorosone-induced cytotoxic effects on pancreatic cancer cells reveals activation of the unfolded protein response (UPR). Br J Pharmacol. 2011 Mar;162(5):1045-1059. PMID: 21091652. Camargo MS, Prieto AM, Resende FA, et al. Evaluation of estrogenic, antiestrogenic and genotoxic activity of nemorosone, the major compound found in brown Cuban propolis. BMC Complement Altern Med. 2013 Jul 31;13:201. PMID: 23902919.