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ProductsBack/Neoxaline [71812-10-7]
Chemical Structure
Chemical Structure
Chemical Structure

Neoxaline [71812-10-7]

Research Use Only
AG-CN2-0154
AdipoGen Life Sciences
CAS Number71812-10-7
DownloadMSDS
Product group Chemicals
Estimated Purity>97%
Molecular Weight435.5
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Neoxaline [71812-10-7]
  • Delivery Days Customer
    10
  • CAS Number
    71812-10-7
  • Certification
    Research Use Only
  • Estimated Purity
    >97%
  • Hazard Information
    Warning
  • Molecular Formula
    C23H25N5O4
  • Molecular Weight
    435.5
  • Scientific Description
    Antimitotic. Cell cycle inhibitor at the G2/M phase [3, 4]. Antiproliferative [3]. Weak CNS stimulant with weak inhibitory activity on blood platelet aggregation [1, 2]. Mycotoxin [1]. - Chemical. CAS: 71812-10-7. Formula: C23H25N5O4. MW: 435.5. Isolated from Aspergillus japonicus Fg-551. Antimitotic. Cell cycle inhibitor at the G2/M phase. Antiproliferative. Weak CNS stimulant with weak inhibitory activity on blood platelet aggregation. Mycotoxin.
  • SMILES
    CON1C2=C(C=CC=C2)C2(CC(O)C(=O)N3\C(=C\C4=CNC=N4)C(=O)NC123)C(C)(C)C=C
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • Neoxaline, a new alkaloid produced by Aspergillus japonicus. Production, isolation and properties: A. Hirano, et al.; J. Antibiot. 32, 781 (1979)
  • Oxaline and Neoxaline: Y. Konda, et al.; Chem. Pharm. Bull. 28, 2987 (1980)
  • Oxaline, a fungal alkaloid, arrests the cell cycle in M phase by inhibition of tubulin polymerization.: Y. Koizumi, et al.; Biochim. Biophys. Acta 1693, 47 (2004)
  • Efficient total synthesis of novel bioactive microbial metabolites: T. Sunazuka, et al.; Acc. Chem. Res. 41, 302 (2008)