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CgoaEGY7SxiEKY-KAAAAAM8CkBk442.png
CgoaEGY7SxiEKY-KAAAAAM8CkBk442.png
CgoaEGY7SxiEKY-KAAAAAM8CkBk442.png

NEP [2414276-32-5]

Research Use Only
T40044
TargetMol Chemicals
CAS Number2414276-32-5
DownloadMSDS
Product group Chemicals
Molecular Weight654.63
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    NEP [2414276-32-5]
  • Delivery Days Customer
    16
  • CAS Number
    2414276-32-5
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    NEP
  • Molecular Formula
    C29H31AsN4O5S2
  • Molecular Weight
    654.63
  • Scientific Description
    NEP, a turn-on fluorescent probe employing the intramolecular charge transfer (ICT) mechanism, facilitates the detection of vicinal dithiol-containing proteins (VDPs). Notably, NEP exhibits exceptional selectivity towards VDPs in live cells and in vivo and manifests a robust green fluorescence signal at lambda ex /lambda em =430/535 nm. Furthermore, NEP bears promise for the potential diagnosis and study of parkinsonism.
  • Shelf life instruction
    3 years
  • SMILES
    CCCCN1C(=O)c2cccc3c(NC(=O)OCC4CS[As](S4)c4ccc(NC(=O)CCN)cc4)ccc(C1=O)c23
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Guodong Hu, et al. Decrease of Protein Vicinal Dithiols in Parkinsonism Disclosed by a Monoarsenical Fluorescent Probe. Anal Chem. 2020 Mar 17;92(6):4371-4378.
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