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Neratinib [698387-09-6]

Research Use Only
N1868
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 218,00
5 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Neratinib [698387-09-6]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Scientific Description
    EGFR inhibitor.; HKI-272, WAY-179272
  • Storage Instruction
    Ambient
  • UNSPSC
    12352200

References

  • López-Tarruella S, Jerez Y, Márquez-Rodas I, et al. Neratinib (HKI-272) in the treatment of breast cancer. Future Oncol. 2012 Jun;8(6):671-81. PMID: 22764764. Sánchez-Martín M, Pandiella A. Differential action of small molecule HER kinase inhibitors on receptor heterodimerization: therapeutic implications. Int J Cancer. 2012 Jul 1;131(1):244-52. PMID: 21826647. Wong KK, Fracasso PM, Bukowski RM, et al. A phase I study with neratinib (HKI-272), an irreversible pan ErbB receptor tyrosine kinase inhibitor, in patients with solid tumors. Clin Cancer Res. 2009 Apr 1;15(7):2552-8. PMID: 19318484. Rabindran SK, Discafani CM, Rosfjord EC, et al. Antitumor activity of HKI-272, an orally active, irreversible inhibitor of the HER-2 tyrosine kinase. Cancer Res. 2004 Jun 1;64(11):3958-65. PMID: 1517300.