Neriifolin [466-07-9]

TargetMol Chemicals

Neriifolin [466-07-9]

16

466-07-9

Chemical

Research Use Only

Neriifolin

C30H46O8

534.69

Neriifolin (17beta-Neriifolin), a cardiac glycoside extracted from the unripe fruit of Cerbera manghas, is a Na+K+-ATPase inhibitor with anticancer activity that inhibits cell proliferation by suppressing HOXA9-dependent gene expression and inducing apoptosis in the human acute myeloid cell line, THP-1. Neriifolin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells and can be used in prostate cancer research.

3 years

[H][C@@]1(CC[C@]2(O)[C@]3([H])CC[C@]4([H])C[C@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](OC)[C@@H]1O)C1=CC(=O)OC1

-20°C

12352200