Nesuparib

MedChem Express

Nesuparib [2055357-64-5]

10

2055357-64-5

Research Use Only

99.54

C23H24N6O

400.48

Nesuparib (JPI-547) is the orally active inhibitor for PARP 1/2 and Tankyrase 1/2 that inhibits tankyrases 1, tankyrases 2, and PARP 1 with IC50s of 5, 1 and 2 nM, respectively. Nesuparib exhibits antitumor activity and can be used in research of advanced solid tumor[1][2][3].

N#CC1=CN=C(N2CCN(CC2)CC3=CC(NC(C4=C5NCCC4)=O)=C5C=C3)C=C1

-20°C,2°C to 8°C

12352200