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Neurofilament (H+L)(NF421 + NFL736), CF405S conjugate, 0.1mg/mL [26628-22-8]

Neurofilament (H+L)(NF421 + NFL736), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC040756
Biotium
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Chicken, Human, Mouse, Porcine, Rat
TargetNEFH
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Overview

  • Supplier
    Biotium
  • Product Name
    Neurofilament (H+L)(NF421 + NFL736), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    NF421 + NFL/736
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID4744
  • Target name
    NEFH
  • Target description
    neurofilament heavy chain
  • Target synonyms
    200 kDa neurofilament protein; CMT2CC; neurofilament heavy polypeptide; neurofilament triplet H protein; neurofilament, heavy polypeptide 200kDa; NFH; NF-H
  • Host
    Mouse
  • Isotype
    IgG
  • Protein IDP12036
  • Protein Name
    Neurofilament heavy polypeptide
  • Scientific Description
    This MAb reacts with a 200 kDa and 68 kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H & NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Chicken, Human, Mouse, Porcine, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203