More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/Neuroprotective agent 5

Neuroprotective agent 5

Research Use Only
HY-169103
MedChem Express
Molecular Weight291.28
Product group Chemicals
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    MedChem Express
  • Product Name
    Neuroprotective agent 5
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Molecular Formula
    C14H14FN3O3
  • Molecular Weight
    291.28
  • Scientific Description
    Neuroprotective agent 5 (compound 28) is a brain permeabilizing agent with anti-neuritis, anti-oxidative damage and neuroprotective effects. Neuroprotective agent 5 exhibits a potent NO inhibitory effect (EC50=0.49 microM), inhibits the release of proinflammatory factors PGE2 and TNF-alpha, downregulates the expression of iNOS and COX-2 proteins, and promotes the polarization of BV-2 cells from the proinflammatory M1 phenotype to the anti-inflammatory M2 phenotype. In addition, Neuroprotective agent 5 can also inhibit acetylcholinesterase (AChE) activity and Abeta42 aggregation in a dose-dependent manner. Neuroprotective agent 5 can be used for the study of Alzheimers disease[1].
  • SMILES
    FCCO/N=C(CN1C=CN=C1)/C2=CC(OCO3)=C3C=C2
  • UNSPSC
    12352200