NF-kappaB-IN-11
HY-155998
Estimated Purity98.42
Product group Chemicals
Molecular Weight326.34
Overview
- SupplierMedChem Express
- Product NameNF-kappaB-IN-11
- Delivery Days Customer14
- CertificationResearch Use Only
- Estimated Purity98.42
- Molecular FormulaC19H18O5
- Molecular Weight326.34
- Scientific DescriptionNF-kappaB-IN-11 (Compound 3i) is a NF-kappaB inhibitor. NF-kappaB-IN-11 inhibits TNF-alpha induced activation of NF-kappaB pathway, and inhibits nuclear translocation of NF-kappaB. NF-kappaB-IN-11 down-regulates the expression levels of phosphor-IKK, IkappaBalpha, and NF-kappaB p65. NF-kappaB-IN-11 has anti-inflammatory activity, and alleviates dextran sulfate sodium-induced colitis in mice. NF-kappaB-IN-11 (p.o.) shows a MTD more than 1852 mg/kg in mice acute toxicity assay [1] .
- SMILESO=C(C1=C(C2OC1CC2C#CC3=CC=C(C)C=C3)C(OC)=O)OC
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200