NFAT Luciferase Reporter-RAW264.7 Cell Line

Boster Bio

NFAT Luciferase Reporter-RAW264.7 Cell Line

9

Functional Assay

Research Use Only

The NFAT Luciferase Reporter cell line is a stably transfected RAW264.7 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the Nuclear Factor of Activated T-cells (NFAT) response element, so that the cell line is designed to measure the transcriptional activity of NFAT. NFAT is a transcription factor originally found in activated T lymphocytes, and is now known to regulate not only T cell activation and differentiation but also the function of other immune cells including dendritic cells, B cells and megakaryocytes. The NFAT induction by calcium ionophore A23187 is shown in Figure 1.

Liquid Nitrogen

12352207