NFIA Antibody / Nuclear Factor 1 A

Biorbyt

NFIA Antibody / Nuclear Factor 1 A

10

Optimal dilution of the NFIA antibody should be determined by the researcher.

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml FACS, IF, IHC-P, WB

Research Use Only

Monoclonal

PCRP-NFIA-2C6

Unconjugated

NFIA

nuclear factor I A

BRMUTD; CCAAT-box-binding transcription factor; CTF; NF1-A; NF-I/A; NFI-A; NFI-L; nuclear factor 1 A-type; TGGCA-binding protein

Mouse

IgG2c

Nuclear factor 1 A-type

Nuclear factor (NF) proteins are a family of CCAAT-box-binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA-binding domain, and activates transcription through a putatively novel, proline-rich, carboxy-terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, -globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.

Human

-20°C,2°C to 8°C

12352203