NFkappaB-p65 Polyclonal Antibody

Reddot Biotech

NFkappaB-p65 Polyclonal Antibody

5

Western Blot, ELISA

Research Use Only

Polyclonal

0.4 mg/ml

Unconjugated

RELA

RELA proto-oncogene, NF-kB subunit

CMCU; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NFKB3; nuclear factor NF-kappa-B p65 subunit; nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A

Rabbit

IgG

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

Human, Mouse

-20°C

12352203