Western blot analysis of extracts from HuvEc cells, using IkappaB-alpha antibody.
Western blot analysis of extracts from HuvEc cells, using IkappaB-alpha antibody.
NFKBIA Antibody
CSB-PA125146
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetNFKBIA
Overview
- SupplierCusabio
- Product NameNFKBIA Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4792
- Target nameNFKBIA
- Target descriptionNFKB inhibitor alpha
- Target synonymsEDAID2; IkappaBalpha; I-kappa-B-alpha; IKBA; ikB-alpha; MAD-3; major histocompatibility complex enhancer-binding protein MAD3; NF-kappa-B inhibitor alpha; NFKBI; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
- HostRabbit
- IsotypeIgG
- Protein IDP25963
- Protein NameNF-kappa-B inhibitor alpha
- Scientific DescriptionInhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. Haskill S., Cell 65:1281-1289(1991). Jungnickel B., J. Exp. Med. 191:395-402(2000). Liu B., Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC12352203