NFKBIB Monoclonal Antibody

Reddot Biotech

NFKBIB Monoclonal Antibody

5

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

1 mg/ml

Unconjugated

NFKBIB

NFKB inhibitor beta

ikappaBbeta; I-kappa-B-beta; IKBB; ikB-B; ikB-beta; NF-kappa-B inhibitor beta; NF-kappa-BIB; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta; thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP9; TRIP-9

Mouse

IgG

Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

Human, Mouse, Rat

-20°C

12352203