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ProductsBack/NGEF Antibody, Biotin conjugated

NGEF Antibody, Biotin conjugated

Research Use Only
CSB-PA850809LD01HU
Cusabio
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetNGEF
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    Cusabio
  • Product Name
    NGEF Antibody, Biotin conjugated
  • Delivery Days Customer
    20
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Biotin
  • Gene ID25791
  • Target name
    NGEF
  • Target description
    neuronal guanine nucleotide exchange factor
  • Target synonyms
    ARHGEF27; EPHEXIN; ephexin1; ephexin-1; eph-interacting exchange protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ8N5V2
  • Protein Name
    Ephexin-1
  • Scientific Description
    Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203