NGEF Antibody, HRP conjugated
CSB-PA850809LB01HU
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetNGEF
Overview
- SupplierCusabio
- Product NameNGEF Antibody, HRP conjugated
- Delivery Days Customer20
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateHRP
- Gene ID25791
- Target nameNGEF
- Target descriptionneuronal guanine nucleotide exchange factor
- Target synonymsARHGEF27; EPHEXIN; ephexin1; ephexin-1; eph-interacting exchange protein
- HostRabbit
- IsotypeIgG
- Protein IDQ8N5V2
- Protein NameEphexin-1
- Scientific DescriptionActs as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203