NGF Receptor Antibody / p75NTR / CD271
ORB639828
ApplicationsImmunoHistoChemistry
Product group Antibodies
Overview
- SupplierBiorbyt
- Product NameNGF Receptor Antibody / p75NTR / CD271
- Delivery Days Customer16
- ApplicationsImmunoHistoChemistry
- Applications SupplierImmunohistochemistry (FFPE): 1-2ug/ml (not suitable for frozen sample testing),Western blot: 1-2ug/ml IHC-P, WB
- CertificationResearch Use Only
- Clone IDrNGFR/1965
- IsotypeIgG
- Scientific DescriptionIt recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
- UNSPSC12352203