NGFR (Nerve Growth Factor Receptor)(NGFR5), CF405S conjugate, 0.1mg/mL [26628-22-8]

Biotium

NGFR (Nerve Growth Factor Receptor)(NGFR5), CF405S conjugate, 0.1mg/mL

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

NGFR5

0.1 mg/ml

Other Conjugate

NGFR

nerve growth factor receptor

CD271; Gp80-LNGFR; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; p75(NTR); p75NTR; TNFR superfamily, member 16; TNFRSF16; tumor necrosis factor receptor superfamily member 16

Mouse

IgG1

Tumor necrosis factor receptor superfamily member 16

This antibody recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Feline, Ferret, Human, Monkey, Mouse, Primate, Rabbit

2°C to 8°C

12352203