NH2-methylpropanamide-Exatecan TFA [1817857-35-4]

TargetMol Chemicals

NH2-methylpropanamide-Exatecan TFA [1817857-35-4]

16

Chemical

Research Use Only

NH2-methylpropanamide-Exatecan TFA

C30H30F4N4O7

634.58

Exatecan TFA, a methylpropanamide-modified derivative of the common ADC cytotoxin Exatecan, serves as a DNA topoisomerase I inhibitor with an IC50 of 2.2 microM (0.975 microg/mL), utilized in the synthesis of ADCs for cancer research [1].

3 years

C(C(O)=O)(F)(F)F.N(C([C@H](CN)C)=O)[C@@H]1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6

-20°C

12352200