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NI-57

NI-57

TQ0083
TargetMol Chemicals
CAS Number1883548-89-7
Product group Chemicals
Molecular Weight383.42
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    NI-57
  • Delivery Days Customer
    9
  • CAS Number
    1883548-89-7
  • Category Supplier
    Chemical
  • Chemical Name
    NI-57
  • Molecular Formula
    C19H17N3O4S
  • Molecular Weight
    383.42
  • Scientific Description
    NI-57 is an inhibitor of proteins of bromodomain and plant homeodomain finger-containing (BRPF) family, with IC50s of 3.1, 46 and 140 nM for BRPF1, BRPF2 (BRD1) and BRPF3, respectively.
  • Shelf life instruction
    3 years
  • SMILES
    CN1C=2C(=CC(NS(=O)(=O)C3=C(OC)C=C(C#N)C=C3)=CC2)C=C(C)C1=O
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Igoe N, et al. Design of a Chemical Probe for the Bromodomain and Plant Homeodomain Finger-Containing (BRPF) Family of Proteins. J Med Chem. 2017 Aug 24;60(16):6998-7011.
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