Nicergoline [27848-84-6]
N3210
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameNicergoline [27848-84-6]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- Formatsoluble in DMSO; alcohol, chloroform, and acetone
- Scientific DescriptionErgot derivative found in Claviceps; alfa1-adrenergic antagonist.; Nicotergoline; Nimergoline; Nimergoline base; Nicergolinum
- Storage Instruction4°C
- UNSPSC12352200
References
- Nishiyama Y, Abe A, Ueda M, et al. Nicergoline increases serum substance P levels in patients with an ischaemic stroke. Cerebrovasc Dis. 2010 Jan;29(2):194-8. PMID: 20029189. Schardl CL, Panaccione DG, Tudzynski P. Ergot alkaloids--biology and molecular biology. Alkaloids Chem Biol. 2006;63:45-86. PMID: 17133714. Mizuno T, Kuno R, Nitta A, et al. Protective effects of nicergoline against neuronal cell death induced by activated microglia and astrocytes. Brain Res. 2005 Dec 20;1066(1-2):78-85. PMID: 16325157. Nishida A, Iwata H, Kudo Y, et al. Nicergoline enhances glutamate uptake via glutamate transporters in rat cortical synaptosomes. Biol Pharm Bull. 2004 Jun;27(6):817-20. PMID: 15187425. Fioravanti M, Flicker L. Efficacy of nicergoline in dementia and other age associated forms of cognitive impairment. Cochrane Database Syst Rev. 2001;(4):CD003159. PMID: 11687175. Alvarez-Guerra M, Bertholom N, Garay RP. Selective blockade by nicergoline of vascular responses elicited by stimulation of alpha 1A-adrenoceptor subtype in the rat. Fundam Clin Pharmacol. 1999;13(1):50-8. PMID: 10027088.