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ProductsBack/Niflumic Acid [4394-00-7]

Niflumic Acid [4394-00-7]

Research Use Only
N3322
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 124,00
10 g
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Niflumic Acid [4394-00-7]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Format
    Soluble in DMSO, ethanol, methanol or acetonitrile.
  • Scientific Description
    NSAID; NMDA inverse agonist, T-type Ca2+ and Cl- channel blocker, GABA-A antagonist, COX-1/2 inhibitor.; Actol, Forenol, Nifluril
  • Storage Instruction
    Hygroscopic.; Ambient
  • UNSPSC
    12352200

References

  • Balderas E, Ateaga-Tlecuitl R, Rivera M, et al. Niflumic acid blocks native and recombinant T-type channels. J Cell Physiol. 2012 Jun;227(6):2542-55. PMID: 21898399. Chi Y, Li K, Yan Q, et al. Nonsteroidal anti-inflammatory drug flufenamic acid is a potent activator of AMP-activated protein kinase. J Pharmacol Exp Ther. 2011 Oct;339(1):257-66. PMID: 21765041. Sinkkonen ST, Mansikkamäki S, Möykkynen T, et al. Receptor subtype-dependent positive and negative modulation of GABA(A) receptor function by niflumic acid, a nonsteroidal anti-inflammatory drug. Mol Pharmacol. 2003 Sep;64(3):753-63. PMID: 12920213. Lerma J, Martín del Río R. Chloride transport blockers prevent N-methyl-D-aspartate receptor-channel complex activation. Mol Pharmacol. 1992 Feb;41(2):217-22. PMID: 1371581.