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Nilotinib [641571-10-0]

Research Use Only
N3346
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 544,00
100 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Nilotinib [641571-10-0]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Scientific Description
    Phenylamino pyridine; Abl, c-Kit, PDGFR, PP2A inhibitor.; AMN 107, Tasigna
  • Storage Instruction
    Ambient
  • UNSPSC
    12352200

References

  • Shaker ME, Ghani A, Shiha GE, et al. Nilotinib induces apoptosis and autophagic cell death of activated hepatic stellate cells via inhibition of histone deacetylases. Biochim Biophys Acta. 2013 Aug;1833(8):1992-2003. PMID: 23499874. Yu HC, Lin CS, Tai WT, et al. Nilotinib induces autophagy in hepatocellular carcinoma through AMPK activation. J Biol Chem. 2013 Jun 21;288(25):18249-59. PMID: 23677989. El-Agamy DS. Anti-allergic effects of nilotinib on mast cell-mediated anaphylaxis like reactions. Eur J Pharmacol. 2012 Apr 5;680(1-3):115-21. PMID: 22329898. Fabbro D, Manley PW, Jahnke W, et al. Inhibitors of the Abl kinase directed at either the ATP- or myristate-binding site. Biochim Biophys Acta. 2010 Mar;1804(3):454-62. PMID: 20152788. Quintás-Cardama A, Cortes J. Nilotinib: a phenylamino-pyrimidine derivative with activity against BCR-ABL, KIT and PDGFR kinases. Future Oncol. 2008 Oct;4(5):611-21. PMID: 18922118.