Nitracrine

MedChem Express

Nitracrine [4533-39-5]

5

4533-39-5

Research Use Only

97.76

C18H20N4O2

324.38

Nitracrine inhibits RNA synthesis and covalently, reversibly binds to DNA but also forms covalent adducts with DNA in vivo. Nitracrine, a 1-nitroacridine derivative, is a potent hypoxia-selective agent in vitro and antitumor agent. Nitracrine has cytotoxicity towards most cells[1][2][3].

O=[N+](C1=CC=CC2=NC3=CC=CC=C3C(NCCCN(C)C)=C21)[O-]

-20°C

12352200