Nitracrine (dihydrochloride hydrate)

MedChem Express

Nitracrine (dihydrochloride hydrate)

5

Research Use Only

C18H24Cl2N4O3

415.31

Nitracrine (dihydrochloride hydrate) inhibits RNA synthesis and covalently, reversibly binds to DNA but also forms covalent adducts with DNA in vivo. Nitracrine (dihydrochloride hydrate), a 1-nitroacridine derivative, is a potent hypoxia-selective agent in vitro and antitumor agent. Nitracrine (dihydrochloride hydrate) has cytotoxicity towards most cells[1][2][3].

CN(C)CCCNC1=C(C([N+]([O-])=O)=CC=C2)C2=NC3=C1C=CC=C3.Cl.O.Cl

12352200