Nivalenol [23282-20-4]
N3584
Estimated Purity≥99%, TLC
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameNivalenol [23282-20-4]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥99%, TLC
- FormatDMSO, Methanol, dichloromethane. Slightly soluble in water.
- Scientific DescriptionTrichothecene mycotoxin produced by Fusarium; peptide chain initiation inhibitor.
- Storage Instruction-20°C
- UNSPSC12352200
References
- Alassane-Kpembi I, Kolf-Clauw M, Gauthier T, et al. New insights into mycotoxin mixtures: the toxicity of low doses of Type B trichothecenes on intestinal epithelial cells is synergistic. Toxicol Appl Pharmacol. 2013 Oct 1;272(1):191-8. PMID: 23735874. Wu W, Flannery BM, Sugita-Konishi Y, et al. Comparison of murine anorectic responses to the 8-ketotrichothecenes 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, fusarenon X and nivalenol. Food Chem Toxicol. 2012 Jun;50(6):2056-61. PMID: 22465835. Nagashima H, Kushiro M, Nakagawa H. Nuclear factor-kappaB inhibitors alleviate nivalenol-induced cytotoxicity in HL60 cells. Environ Toxicol Pharmacol. 2011 Jan;31(1):258-61. PMID: 21787693. Marzocco S, Russo R, Bianco G, et al. Pro-apoptotic effects of nivalenol and deoxynivalenol trichothecenes in J774A.1 murine macrophages. Toxicol Lett. 2009 Aug 25;189(1):21-6. PMID: 19410639. Nasri T, Bosch RR, Voorde St, et al. Differential induction of apoptosis by type A and B trichothecenes in Jurkat T-lymphocytes. Toxicol In Vitro. 2006 Sep;20(6):832-40. PMID: 16472964. Cundliffe E, Cannon M, Davies J. Mechanism of inhibition of eukaryotic protein synthesis by trichothecene fungal toxins. Proc Natl Acad Sci U S A. 1974 Jan;71(1):30-4. PMID: 4521056.