NKCC2 antibody

Biorbyt

NKCC2 antibody

16

1 microg/ml of SPC-401 was sufficient for detection of NKCC2 in 10 microg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

Western Blot, ImmunoHistoChemistry

WB (1:1000); IHC (1:25) IHC, WB

Research Use Only

Polyclonal

1 mg/ml

APC

Slc12a1

solute carrier family 12 member 1

BSC1; bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1; bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2; kidney-specific Na-K-Cl symporter; Nkcc2; solute carrier family 12 (sodium/potassium/chloride transporter), member 1; solute carrier family 12 (sodium/potassium/chloride transporters), member 1; solute carrier family 12 member 1; Solute carrier family 12, member 1 (bumetanide-sensitive sodium-[potassium]-chloride cotransporter)

Rabbit

RCG26347, isoform CRA_c

Rabbit polyclonal to NKCC2 (APC). NKCC2, a kidney-specific member of the cation chloride co-transporter family SLC12, facilitates transport of sodium, potassium, and chloride ions from the lumen of the renal thick ascending limb into the cell. Transport of sodium dilutes the luminal fluid, decreasing its osmolality creating an osmotic driving force for water reabsorption in the connecting tubule and cortical collecting duct under the influence of the hormone vasopressin. NKCC2 is found on the apical surface of the thick ascending limb of the loop of Henle and is blocked by loop diuretics such as furosemide..

Human, Mouse, Rat

2°C to 8°C

12352203