NKL 22
HY-100384
Overview
- SupplierMedChem Express
- Product NameNKL 22 [537034-15-4]
- Delivery Days Customer5
- CAS Number537034-15-4
- Estimated Purity97.27
- Molecular FormulaC19H23N3O2
- Molecular Weight325.40
- Scientific DescriptionNKL 22 (compound 4b) is a potent and selective inhibitor of histone deacetylases (HDAC) , with an IC 50 of 199 and 69 nM for HDAC1 and HDAC3 , respectively. NKL 22 exhibits selectivity over HDAC2/4/5/7/8 (IC 50 ≥1.59 microM). NKL 22 ameliorates the disease phenotype and transcriptional abnormalities in Huntingtons disease transgenic mice [1] [2] [3] .
- SMILESO=C(NC1=CC=CC=C1N)CCCCCC(NC2=CC=CC=C2)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200