NKX2-1 Polyclonal Antibody

Reddot Biotech

NKX2-1 Polyclonal Antibody

5

Western Blot, ELISA

Research Use Only

Polyclonal

0.2 mg/ml

Unconjugated

NKX2-1

NK2 homeobox 1

BCH; BHC; homeobox protein NK-2 homolog A; homeobox protein Nkx-2.1; NK-2; NK-2 homolog A; NKX2.1; NKX2A; NMTC1; T/EBP; TEBP; thyroid nuclear factor 1; thyroid transcription factor 1; thyroid-specific enhancer-binding protein; TITF1; TTF1; TTF-1

Rabbit

IgG

This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias TFF1 with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.

Human, Mouse, Rat

-20°C

12352203