![NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (NX2/1422R), CF640R conjugate, 0.1mg/mL [26628-22-8] NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (NX2/1422R), CF640R conjugate, 0.1mg/mL [26628-22-8]](https://biotium.com/wp-content/uploads/2018/09/view_image-30.jpeg)
NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (NX2/1422R), CF640R conjugate, 0.1mg/mL [26628-22-8]
BNC401422
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Rabbit
TargetNKX2-2
Overview
- SupplierBiotium
- Product NameNKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (NX2/1422R), CF640R conjugate, 0.1mg/mL
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDNX2/1422R
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID4821
- Target nameNKX2-2
- Target descriptionNK2 homeobox 2
- Target synonymshomeobox protein NK-2 homolog B; homeobox protein Nkx-2.2; NK2 transcription factor related, locus 2; NK2 transcription factor-like protein B; NKX2.2; NKX2B
- HostRabbit
- IsotypeIgG
- Protein IDO95096
- Protein NameHomeobox protein Nkx-2.2
- Scientific DescriptionExpression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Human, Rabbit
- Storage Instruction2°C to 8°C
- UNSPSC12352203