NLRP3-IN-55

MedChem Express

NLRP3-IN-55

9

Research Use Only

C32H30ClFN2O4

561.04

NLRP3-IN-55 (Compound 19) is a potent NLRP3 inhibitor (IC50 = 0.34 microM). NLRP3-IN-55 directly targets the NLRP3 protein (KD = 0.45 microM), blocking the assembly and activation of the NLRP3 inflammasome, leading to anti-inflammatory effects and inhibition of cellular pyroptosis[1].

CCC(NC1=CC=C(C=C1)C2=CC=CC=C2N(C(C3=CC=C(C=C3)F)=O)CC4=CC(Cl)=CC=C4OCCOC)=O

12352200