NMac1 [1332290-68-2]

TargetMol Chemicals

NMac1 [1332290-68-2]

72

Chemical

Research Use Only

NMac1

C24H28O4

380.48

NMac1is a small molecule phenylbutenoid dimer that has novel anti-proliferative effect only under glucose starvation in metastatic breast cancer cells. NMac1 causes significant activation of AMPK by decreasing ATP synthesis, lowers mitochondrial membrane potential (MMP, deltapsim), and inhibits oxygen consumption rate (OCR) under glucose starvation. These effects of NMac1 are provoked by a consequence of OXPHOS complex I inhibition.

3 years

C(=C/C1=CC(OC)=C(OC)C=C1)\C2C(C=CCC2)C3=CC(OC)=C(OC)C=C3

-20°C

12352200