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ProductsBack/NMDAR1 antibody

NMDAR1 antibody

GTX133097
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityCanine, Mouse, Rat
TargetGrin1
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Overview

  • Supplier
    GeneTex
  • Product Name
    NMDAR1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.37 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID14810
  • Target name
    Grin1
  • Target description
    glutamate receptor, ionotropic, NMDA1 (zeta 1)
  • Target synonyms
    GluN1; GluRdelta1; GluRze; GluRzeta1; glutamate [NMDA] receptor subunit zeta-1; glutamate receptor ionotropic, NMDA 1; M100174; N; Nm; NMD; Nmdar; NMDAR1; NMD-R1; N-methyl-D-aspartate receptor subunit NR1; NR1; Rgsc1; Rgsc174
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP35438
  • Protein Name
    Glutamate receptor ionotropic, NMDA 1
  • Scientific Description
    NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Modulated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.
  • Reactivity
    Canine, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Impact of NMDA receptor activation on DNA damage in PC12 neuron-like cell cultures in the presence of beta-amyloid peptides.
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  • Alleviative Effect of Alpha-Lipoic Acid on Cognitive Impairment in High-Fat Diet and Streptozotocin-Induced Type 2 Diabetic Rats. Ko CY et al., 2021, Front Aging Neurosci
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  • Modulating disease-relevant tau oligomeric strains by small molecules. Lo Cascio F et al., 2020 Oct 30, J Biol Chem
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  • Impact of Repetitive Mild Traumatic Brain Injury on Behavioral and Hippocampal Deficits in a Mouse Model of Chronic Stress. Algamal M et al., 2019 Sep 1, J Neurotrauma
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  • Gut microbe-derived metabolite trimethylamine N-oxide activates the cardiac autonomic nervous system and facilitates ischemia-induced ventricular arrhythmia via two different pathways. Meng G et al., 2019 Jun, EBioMedicine
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