NNK [64091-91-4]

MedChem Express

NNK [64091-91-4]

10

64091-91-4

Research Use Only

99.98

C10H13N3O2

207.23

NNK is a nicotine-nitrosated derivative. NNK simultaneously stimulates Bcl2 phosphorylation exclusively at Ser70 and c-Myc at Thr58 and Ser62 through activation of both ERK1/2 and PKCalpha[1]. NNK induces survival and proliferation of human lung cancer cells. NNK can be used for lung cancer mice model structure[2].

O=C(C1=CC=CN=C1)CCCN(C)N=O

-20°C

12352200