Nobiletin [478-01-3]

Yoshigai E, Machida T, Okuyama T, et al. Citrus nobiletin suppresses inducible nitric oxide synthase gene expression in interleukin-1bèta-treated hepatocytes. Biochem Biophys Res Commun. 2013 Sep 13;439(1):54-9. PMID: 23958298. Nakajima A, Aoyama Y, Nguyen TT, et al. Nobiletin, a citrus flavonoid, ameliorates cognitive impairment, oxidative burden, and hyperphosphorylation of tau in senescence-accelerated mouse. Behav Brain Res. 2013 Aug 1;250:351-60. PMID: 23714077. Ma X, Jin S, Zhang Y, et al. Inhibitory Effects of Nobiletin on Hepatocellular Carcinoma In Vitro and In Vivo. Phytother Res. 2013 Jul 1. [Epub ahead of print]. PMID: 23818450. Aoki K, Yokosuka A, Mimaki Y, et al. Nobiletin induces inhibitions of Ras activity and mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signaling to suppress cell proliferation in C6 rat glioma cells. Biol Pharm Bull. 2013;36(4):540-7. PMID: 23546290. Lee YS, Cha BY, Choi SS, et al. Nobiletin improves obesity and insulin resistance in high-fat diet-induced obese mice. J Nutr Biochem. 2013 Jan;24(1):156-62. PMID: 22898571. Baek SH, Kim SM, Nam D, et al. Antimetastatic effect of nobiletin through the down-regulation of CXC chemokine receptor type 4 and matrix metallopeptidase-9. Pharm Biol. 2012 Oct;50(10):1210-8. PMID: 22853317.