NOD1 Polyclonal Antibody

Reddot Biotech

NOD1 Polyclonal Antibody

5

ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

NOD1

nucleotide binding oligomerization domain containing 1

CARD4; caspase recruitment domain family, member 4; caspase recruitment domain-containing protein 4; CLR7.1; NLR family, CARD domain containing 1; NLRC1; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1; nucleotide-binding oligomerization domain-containing protein 1

Rabbit

IgG

This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5 UTR have been described, but the full-length nature of these variants has not been determined.

Human, Mouse, Rat

-20°C

12352203